The 5-HT7 receptor is a member of the GPCR superfamily of cell surface receptors and is activated by the neurotransmitter serotonin. The 5-HT7 receptor is expressed in a variety of tissues, particularly in the brain, the gastrointestinal tract, and various blood vessels. The 5-HT7 receptor plays a role in smooth muscle relaxation within the vasculature and in the gastrointestinal tract, and is involved in thermoregulation, circadian rhythm, learning and memory, and sleep. This receptor is also involved in mood regulation, suggesting that it may be a useful target in the treatment of depression.
s://creative-bioarray/acroscell/human-htr7-gs-stable-cell-line-cho-acc-rg0570-item-370